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The BIOFIRE System and Your Immune System

The BIOFIRE System provides syndromic infectious disease testing, which allows healthcare providers to choose the right test, the first time. Patients benefit from quicker diagnosis and more targeted therapy. Clinicians benefit from improved stewardship for antibiotics. Labs save money and increase efficiency.

The BioFire FilmArray Pneumonia plus panel (PN panel) examines native sputum, endotracheal aspirate, and bronchoalveolar lavage specimens (including mini-BAL) for 33 pathogens that are clinically relevant and antimicrobial resistance genes with semiquantitative results in about an hour.

Respiratory

The burning of biomass (wood plants, trees and other organic materials) produces gaseous pollutants and fine particulate matter that negatively impact the respiratory system. Climate change can make it more difficult to reverse the negative impacts of forest fires on human health.

In the United States, wildfire smoke has been associated with hospitalizations for respiratory illnesses, including asthma, COPD and lung cancer. This kind of air pollution also increases the risk of cardiovascular disease and is a major contributor to the burden on disease among the most vulnerable populations.

In the COVID-19 pandemic, many communities were exposed to harmful levels of air pollution due to wildfires. The response of public health has been limited to a public education campaign about symptom management. This knowledge gap is alarming given the evidence that smoking cigarettes and other sources of air pollution can lead to health issues.

Researchers are currently assessing the best way to safeguard public's health during any future incidents of this type. NIH invests in research on this critical public health issue through the BLUE CORAL and FIRE CORAL studies.

For the first time, a prospective study will examine the long-term effects of exposure to smoke from wildfires and other sources. FIRE CORAL recruits adult participants who are hospitalized for COVID-19 index episodes and speak English or Spanish however, they are not pregnant. The FIRE CORAL protocol includes a set of tests in-person that objectively measure the pulmonary function test and lung imaging as well as functional assessment.

Smoke and other particles can cause or worsen respiratory conditions such as emphysema, COPD and pneumonia. A variety of steps can be taken to prevent or reduce the adverse health effects resulting from exposures to smoke, including abstaining from outdoor activities when it is feasible and wearing the EPA's "N95" mask, which is designed to trap fine particles.

Smoking can cause irritation of the eyes and throat, and lead to an irritated nose. To lessen the effects the lungs need to be flushed by drinking lots of water and taking medicines that decrease inflammation, like corticosteroids.

Bloodstream

Your bloodstream is on the front lines of fighting germs that invade your body. Dendritic cells are specialized cells that are akin to your bioethanol fire bowl department's call centre; they take antigens (molecules that trigger an immune response) from invading germs and then release proteins that alert other white blood cells to come fight them. Circulating total white blood cell counts, differentials and band Bio fuel Fireplace cells were elevated after firefighters' firefighting shifts, as compared to levels after strenuous physical exertion without fire-fighting.

Skin

Dermatologists were concerned about the smoke and ash of the California wildfires could cause an adverse effect on the skin of those who were exposed to them. Maria Wei, a graduate student at the University of California, Irvine, is studying how extreme fire pollution affects skin. Her research was published in Scientific Reports on April 22nd.

Wei's study shows that the temperature of the skin changes depending on the length of time that the body is exposed. It can take up to two hours for the skin of someone to reach their "flash point"--the place where it begins to burn and turn to ash. It is important to avoid staying near a campfire or fire, and you should always wear protective clothing if outdoors in a humid or hot day.

Forest fires will continue occur, despite the measures taken to prevent the spread of wildfires. Wei is predicting that the number of people suffering from the effects of wildfires will rise as climate change causes more and more forests to burn. This means that more people will need to wear caps and long sleeves as well as thick moisturizers.

Air pollution from wildfires can increase the severity of atopic skin dermatitis which is a condition that causes itchy skin for many people. The particles in smoke can clog pores, making atopic skin worse.

Atopic dermatitis can make people more sensitive to UV light. This is often exacerbated by smoke from wildfires. This can lead to people seeking out tanning salons and tannish with less protection.

A fire and ice treatment can help reduce atopic skin symptoms of dermatitis however, it isn't recommended for anyone with an open wound or rash. This treatment is not recommended for those with active acne, or if you're pregnant or nursing. The IS Clinical bio ethanol inset fire & Ice Facial, at Novuskin Las Vegas' premier membership MedSpa is a results-driven intensive facial that bridges between an easy facelift and a peel, without requiring downtime. It's designed to rejuvenate the skin, alleviate the appearance of rosacea, lessen the appearance of acne scars, reduce wrinkles, and promote the renewal of cells. This is a great treatment to give your skin a radiant glow.

Infections

The human body is made up of a complex set of organs and tissue that work together to guard against infections. Infections are caused by microscopic microorganisms like bacteria, viruses, parasites and fungus that infiltrate healthy cells and cause them to replicate out of control. Your immune system may react by displaying signs of illness. These symptoms can include anything from a stuffy or runny nose to a stomach upset and can include a high fever, swollen glands, and a skin rash. The severity of your symptoms may be affected by the nature of the disease, its location, and even your temperature.

Infections can spread in various ways, but they are most often spread through droplets in the air that remain after a sniff or cough. Bacterial diseases like tuberculosis, strep throat, meningococcal disease, and Legionnaires' disease spread this way, along with some viral infections like the common cold and influenza. Certain bacterial infections like skin infections or sexually transmitted diseases (STIs) such as gonorrhea or chlamydia are spread by direct contact with infected mucous or tissue surfaces, or indirectly through surfaces that are contaminated. Some bacterial diseases are carried by bugs like ticks, mosquitoes or fleas. They can be transmitted when they bite you.

Some parasites and viruses are small bioethanol fire enough to enter your bloodstream and infect your cells, which leads to serious illnesses like the common cold and AIDS. Fungi can trigger skin conditions such as ringworm and athlete's foot and others can infect the respiratory tract and nervous system.

The BioFire Panel uses our innovative FilmArray technology to analyze the sputum and bronchoalveolar fluid samples for a comprehensive listing of pathogens that are involved in upper respiratory infection. The kit includes a reagent bag that contains all the chemistry necessary to perform reverse transcription, nested multiplex PCR and detection in one machine. It's a simple solution to aid clinicians in identifying and treat patients with different respiratory symptoms. The test has been granted an Emergency Use Authorization. It is available in bioMerieux CLIA medium and high complexity labs.